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8 Small amounts of GLP-1 may also be produced by preproglucagon neurons, located in the nucleus tractus solitarii of the brainstem 26,27 and projected to other brain regions, such as the nuclei of the hypothalamus, including the arcuate and paraventricular nuclei

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20 There is one early blinded, placebo-controlled trial of NAC on its own in 43 patients with Alzheimers disease that found NAC, 50 mg per kg bodyweight (equivalent to 3750 mg for a person weighing 75 kg) per day for 6 months, to be superior to placebo in almost all outcome measures, although not all reached statistical significance